The Blood Type Story

By Dr. D’Adamo

Certain foods, and food groups act like poisons to certain blood types. What can be a medicine for one person, can be a poison for another. How is this possible? Because of genetics.

You were born with a basic blood type. O, A, B, or AB. You got it from your parents genes. Genes have a way of representing a bit of genetic history.

Type O blood is said to be the oldest blood and shows a connection to the hunter-gatherer cultures. This blood type is strongly aligned with high protein consumption in the form of animal meat and individuals with type O blood might generally produce higher stomach acids. This is typically the group that experiences more incidence of gastric ulcer disease than the other groups. Type O’s handle animal protein well but grains like whole wheat, and dairy products are not so good. Type O groups comprise about 46% of the American population.

Blood group A was the next said to evolve and merged with the development of agricultural practices. Blood group A is primarily associated with vegetarian food sources and individuals in that group secrete smaller amounts of stomach acid. Protein requirements are not any less than a group O person but the source is different. Type A’s do poorly with the typical meat and potato fare and are predisposed to heart disease, cancer, and diabetes. Soy proteins, grains, and vegetables are important for type A’s as well as food that is fresh, pure and organic. Group A comprises 42% of the American population. Then there is type B and AB.

The key to all of this is sugar and lectin chemistry. Different blood types are incompatible with different sugars and lectins (proteins) of certain food groups. You will come to understand the importance of blood typing against your dietary history in relationship to the microscopic findings.

It’s the Sugar that Determines the Type
What is responsible for blood type is a sugar that is adsorbed (stuck) to the outside of the red blood cell. For type O blood it is fucose, for type A it is a combination of fucose and N-Acetyl galactosamine, for type B it is fucose and D-Galactose, and type AB is a combo of the sugars for both A and B blood type.

A person’s blood type is not just related to their blood, but to their whole body. Sweat, tears, saliva, all body fluids actually have the same blood type because the sugar is secreted or spread throughout the body. There is an enzyme called fucosyltransferase (FUT) responsible for this secretion. A gene controls this.

Some people have a gene defect (20% of the population) for the production of FUT and hence they have much lower secretion of the blood type sugar in their other fluids. These folks are called non-secretors.

When you are secreting your blood type sugars in sweat, etc., this acts as a protective shield from bacteria, viruses and other microbes. A non-secretor does not have this shield and it takes a bit longer for the body to recognize pathogens. It also means there can be a greater influence of food sensitivities and with a bit more stress on the immune system and more susceptibility for certain illnesses as well.

The sugars responsible for blood type are also found in animals, microorganisms, soil, food. Viruses can have them. When a virus with the same sugar hits an individual with the same sugar blood type, the antigen of the virus gets in the door a little easier as the body sees it as self and the defense system is out to lunch. A household may have multiple blood types people in the house, and when a virus hits, one might get hit a little harder depending on the blood type sugar compatibility.

Transfusion Factor
You may recall that some people cannot have a transfusion of other people’s blood. The blood type of a donor might be incompatible with the blood type of the receiver. Why? Different sugars – and you can refer to them as antigens. If the receiver gets the wrong blood – the foreign antigen/sugar – the body mounts a defense. The antibodies generated will proceed to agglutinate the donated red blood cells together in order to be destroyed, clot masses can form and yikes, the receiver can clot to death.

Blood Type Sugars in Food
Some foods can have blood type antigens as well. Look at milk. It is the secretion of a cow. So what is a cow’s blood type? Well, there is a large amount of D-galactose in milk. That is the type B sugar. So, blood type B people have little issue with milk, not so much for the others. The digestive system handles much. If it didn’t, the milk going in would be like a transfusion with incompatible blood hitting the system. Yes that could be a problem. As it is, there is often an immune response at some level for many when they consume milk due to the incompatibility.

Back to Lectins
The protein molecules that can be incompatible with blood, can stick on binding sites of red blood cells that are designed to stick sugars. What does that mean? Agglutination of your red blood cells.  Result: poor circulation, inability to adequately transfer oxygen from red blood cells to tissues, inflammation. Can this be a problem? You betcha.

Bowel Toxicity

By Elizabeth Clemons

Appearance – A dark, blackish colour occurring in the centre of the dry blood sample, often in many layers, but is most often seen in the last few layers.

Indicative of bowel toxicity, often coupled with digestive insufficiency and/or Candida.
As the immune system is often preoccupied with neutralizing the toxins leaching into the system from the colon, people displaying this sign can have poor immunity.
May be associated with leaky gut syndrome.

Increase intake of raw/live foods and fibre.
Colonic irrigation, Herbal Fibre Blend, juicing.
Supplement to balance the terrain and restore healthy bowel flora.

This is how bowel toxicity and/or candida shows up in Live Blood Analysis. After cross checking for symptoms and other indications – the steps above are usually suggested followed by monitoring the situation.

More information on the bowel and colon:

The Colon/bowel
The final part of the digestive tract, the colon; is about five feet long and has an average diameter of 2 ½ inches.
It must handle the bulk of the food we eat.
Its lining includes sensitive nerves and glands that aid in the assimilation of food, especially vitamins, enzymes and water.
A healthy colon is essential to a healthy body.
When the colon is working properly, its peristaltic (muscular, wave like) motions move food through the system and eliminate unassimilated substances in the form of waste within 16-24 hours of eating.

Effect of a Toxic Colon on the Body
When a bowel is under active, toxic wastes are more likely to be absorbed through the bowel wall and into the bloodstream.
The blood then circulates these toxins to every part of the body and deposits some of them in tissues.
The greatest amounts of these toxins are retained in the constitutionally weakest tissues.
If any other elimination system in the body is under active, more wastes are retained in the body.
As toxins accumulate in the tissues, alterations in cellular functioning takes place, especially in the tissues in which toxins have settled.

In addition, digestion may become poor, with the partially digested material adding to the problems because the body cannot make tissue out of half digested nutrients. When a person reaches the degenerative-disease stage, it is a sign that toxic settlement has taken over a specific part or parts of the body.

This is the time to consider detoxification. A healthy, strong functioning colon is essential to maintaining good health.
The colon, together with the kidneys, lungs and skin are responsible for eliminating waste from the body.

But over time, your colon may lose its ability to properly eliminate all waste from the gastrointestinal tract due to a combination of poor diet, improper food combining, drug intake and/or lifestyle.

Millions of people in this country who suffer all manner of health problems may never even consider that the source of their problems is a toxic, sluggish colon. This is not surprising. The traditional treatment of health disorders, disease symptoms and disease management using pharmaceuticals and surgery may completely obscure the root cause of recurring health problems.

Most people have no idea how much old, hardened, fecal matter is lodged within their colons. Many experts believe that the average person has 5-20 pounds of accumulated waste matter in their colon.

Health Problems
An unhealthy colon can adversely affect your total health, including all your body systems.

Common bowel disorders
Constipation – Over 70 million Americans suffer from bowel problems. The number 2 cause of death in the United States is cancer. Of these, 100,000 give up their lives every year to cancer of the colon. Constipation contributes toward the lowering of body resistance, predisposing it to many acute illnesses and the creation of a great many degenerative and chronic processes. Most people do not drink enough water; they are chronically dehydrated. This causes all body tissues and fluids to become thicker and more viscid. The mucous lining in the colon changes in consistency, failing to provide a slick lubrication for the movement of feces.

Chronic Diarrhea – there are people with chronic diarrhea who say they are not constipated because their bowels move several times per day. Their daily bowel movements are not constipated, but let us look at the cause of their diarrhea. Chronic diarrhea is most often due to the presence of irritation in the colon. As long as the irritating influence is present, the colon attempts to expel it by repeatedly emptying itself of whatever can be forced out. In chronic diarrhea, the accumulation of stagnant mucoid, sometimes laden with harmful bacteria or even parasites, is generally of such a magnitude and nature as to be actively irritating. In this case, the source result is chronic diarrhea. Chronic diarrhea will often respond remarkably to an effective colon-cleansing program.

Parasites – The discussion of diarrhea brings up the question of parasites because chronic diarrhea is often due to the presence of parasites in the system. Intestinal parasites thrive in filthy environments. The many varieties of intestinal worms lodge themselves in the old matter that encrusts the walls of the intestinal tract. Without the presence of stagnant material to embed themselves in, many intestinal parasites cannot maintain a foothold in the body.

Autointoxication – This is the process whereby the body literally poisons itself by maintaining a cesspool of decaying matter in its colon. This inner cesspool can contain as high a concentration of harmful bacteria as a cesspool under a house. The toxins released by the decay process get into the bloodstream and travel to all parts of the body. Every cell in the body gets affected, and many forms of sickness can result. Because it weakens the entire system, autointoxication can be a causative factor for nearly any disease.

Putrefaction – One of the main causes of autointoxication is putrefaction within the intestinal tract. Putrefaction is a process of decay in which foul odors and toxic substances are generated. Ideally, there should be little or no putrefaction happening within the body. That is, daily bowel movements should have very little or no putrefactive odor, and there should be no stagnant putrefactive material within the alimentary tract. The amount of putrefaction present in the body depends upon how long the food undergoing putrefaction has been in the body, upon the efficiency of the digestive processes, and upon what kind of food is undergoing putrefaction. The length of time food stays in the body depends upon two factors-stagnation and transit time.

Stagnation is the failure of matter in the alimentary tract to continue moving until expelled through the anus. When material becomes lodged in the alimentary tract, it can continue to putrefy and release toxins for weeks. Stagnation occurs primarily in the colon and is usually the body’s largest contributor to putrefaction and the consequent autointoxication.

Colitis – This is an irritable bowel condition that is highly associated with psychological distress. Few people truly realize the benefits of a calm and peaceful lifestyle. They are often unaware of the mind’s ability to sink into the body’s functioning ability and upset normal tissue activities. Fear, anger, depression, stress tension, worries and obsessions can all upset delicate processes in the body, and in particular, those of digestion and elimination. Sometimes what we need is a good cerebral laxative to rid the mind of emotional autointoxication and constipation.

Diverticulitis – This particular disease of the colon is occurring at an ever-increasing rate. It is a serious bowel disturbance leading to many difficulties and must be avoided. When the diet is lacking a good diet, the colonic muscle must work extremely hard to force feces through the organ. Where there is weakness in muscle fibers a hernia occurs, producing a small pouch or sac-like protrudence in the tissue. It looks like a blister on the side of a tire where the air is forcing its way to the surface through a weak spot in the tire wall. These sacs, or diverticula’s, are blind in one end. Therefore feces accumulates within them and hold morbid matter in, which a variety of very unfavorable organisms can begin to breed. They become sources of infection, inflammation and degenerative conditions. They are also the host for the production of powerful toxins, adding to an already over-burdened and toxic body. When these diverticula have become inflamed and irritated, we have a case of diverticulitis. Should any one of these festering sacs produce a rupture, and then we have a grave situation in, which life is threatened by the release of these very poisonous substances into the abdominal cavity of the body where infection can spread quite rapidly.

References and recommended reading:
Tissue Cleansing Through Bowel Management, Dr. Bernard Jensen
The Colon Health Handbook, Robert Gray
Dr. Jensen’s Guide to Better Bowel Care, Dr. Bernard Jensen
Colon Health, Dr. N.W. Walker

Bio-Ionic Liquid Mineral Concentrate

The most comprehensive liquid remineralizing and alkalizing formula on the market. Now available at Tranquille Technologies Inc.

Contains a Proprietary Blend of:

  • 72 Liquid Ionic Trace Minerals from Utah’s Great Salt Lake
  • 12 Liquid Biochemic Tissue “cell” Salts
  • Fulvic Mineral Concentrate
  • Potassium Bicarbonate
  • Sodium Bicarbonate
  • Potassium Hydroxide
  • Pink Himalayan Crystal Salt
  • MSM
  • N-Acetyl Cysteine (NAC)
  • Aloe vera 200:1 extract
  • Siberian Ginseng (Eleutherococcus senticosus)
  • Horsetail (Equisetum arvense)
  • Nettle Leaf (Urtica dioica)
  • Structured, Energised & Re-catalysed Water
  • Radionically Energised, Cleansed and Preserved

Key Benefits of the Formula:

  • Rapid impact on blood pathologies
  • Highly alkaline-forming
  • Wide therapeutic and healing spectrum
  • Can be taken on a daily basis, long term with no negative side effects
  • Powerful remineralizing and alkalizing effects
  • Every single trace mineral under the sun
  • All 12 biochemic tissue salts
  • Fulvic acid
  • Scalar energy patterns for health and vitality
  • No interactions and contraindications

Bio-Ionic Mineral Concentrate outperforms all competitors in the same genre of product, providing more volume than competitors at a better price with a far more comprehensive therapeutic spectrum in one single product. It contains a mineral balance very similar to that found in our own blood and tissues. With a proprietary bend of ionic minerals, Biochemic tissue salts, alkaline salts, fulvic acid and other natural ingredients, there is nothing like it on the market today.

Try it and watch the rapid difference in your blood and the impact on your health and well-being!

Ingredients of the New Formula

In essence the formula is a combination of:

  1. 72 Liquid Ionic Trace Minerals from Utah’s Great Salt Lake
  2. 12 Liquid Biochemic Tissue “cell” Salts
  3. Fulvic Mineral Concentrate
  4. Potassium Bicarbonate
  5. Sodium Bicarbonate
  6. Potassium Hydroxide
  7. Pink Himalayan Crystal Salt
  8. MSM
  9. N-Acetyl Cysteine (NAC)
  10. Aloe vera 200:1 extract
  11. Siberian Ginseng (Eleutherococcus senticosus) extract
  12. Horsetail (Equisetum arvense)
  13. Nettle Leaf (Urtica dioica)
  14. Structured, Energised & Re-catalysed Water
  15. Radionically Energised, Cleansed and Preserved

More info here on main ingredients and their application

Free Radical Damage

Posted 3/18/2016

Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation.

Hybertson BM1, Gao BBose SKMcCord JM.


Click here to see the post.


For the past 40 years or so, oxidative stress has been increasingly recognized as a contributing factor in aging and in various forms of pathophysiology generally associated with aging. Our view of oxidative stress has been largely “superoxide-centric”, as we focused on the pathological sources of this oxygen-derived free radical and the types of molecular havoc it can wreak, as well as on the protection provided by the antioxidant enzymes, especially the superoxide dismutases, catalases, and glutathione peroxidases. In the last decade our view of oxidative stresshas broadened considerably, and it is now often seen as an imbalance that has its origins in our genes, and the ways in which gene expression is regulated. At the center of this new focus is the transcription factor called nuclear factor (erythroid-derived 2)-like 2, or Nrf2. Nrf2 is referred to as the “master regulator” of the antioxidant response, modulating the expression of hundreds of genes, including not only the familiar antioxidant enzymes, but large numbers of genes that control seemingly disparate processes such as immune and inflammatory responses, tissue remodeling and fibrosis, carcinogenesis and metastasis, and even cognitive dysfunction and addictive behavior. Thus, the dysregulation of Nrf2-regulated genes provides a logical explanation for the connections, both direct and indirect, between observable oxidative stress and perhaps 200 human diseases involving these various physiological processes, each reflecting a network involving many gene products. The evolutionary self-association of these many genes under the common control of Nrf2 suggests that the immune and inflammatory systems may present the largest demand for increased antioxidant protection, apart from constitutive oxidative stress resulting from mitochondrial oxygen consumption for metabolic purposes. Gene expression microarray data on human primary vascular endothelial cells and on the SK-N-MC human neuroblastoma-derived cell line have been obtained in response to the dietary supplement Protandim, a potent composition of highly synergistic phytochemical Nrf2 activators. Pathway analysis of results shows significant modulation by Protandim of pathways involving not only antioxidant enzymes, but of those related to colon cancer, cardiovascular disease, and Alzheimer disease.

Copyright © 2011 Elsevier Ltd. All rights reserved.
PMID: 22020111
(PubMed – indexed for MEDLINE)

Vitamin D Deficiency

By Dr. Mercola

Nine out of ten Americans may be deficient in Vitamin D and not even know it. Are you getting enough of this vital nutrient? If you are taking a supplement, is it a form your body can easily absorb for optimal benefits?

There are over 34,000 scientific investigations to date on how vitamin D works in your body, yet it continues to be ignored by large segments of the population and even many doctors.

Vitamin D deficiency is often one of the last things a doctor suspects when a patient complains of less-than-perfect health.

If you use optimal levels of vitamin D to gauge a deficiency, you find that approximately 90 percent of people need higher vitamin D levels.

Unfortunately, many people are deficient because they aren’t able to obtain enough vitamin D through direct sunlight and their diet alone, and they aren’t taking a high-quality supplement.

Of those that are supplementing with vitamin D, they are most likely using a form that is not absorbed well by their body, and they aren’t receiving optimal benefits.

Before we take a look at your personal risk level of becoming deficient in vitamin D and I tell you my recommendation to maintain optimal levels, let’s first review why vitamin D is so important to your overall health…

Why Vitamin D Is ESSENTIAL for Your Entire Body

Once thought of as playing a primary role in osteoporosis and osteomalacia, researchers now realize that vitamin D affects virtually every cell and tissue in your body. And it affects numerous vitamin D receptors located throughout your body and nearly 3,000 genes.

Vitamin D is produced when the sun strikes your skin under the right conditions

Your cells need the active form of vitamin D to unlock the genetic blueprints stored inside the cell. Without these crucial blueprints, these aspects of your health could potentially be at risk:

  • Maintenance of overall health*
  • Cellular growth and development*
  • Bone strength and health*
  • Blood sugar health*
  • Digestion and absorption of nutrients*
  • Blood pressure health*
  • Heart health*
  • Vascular system health*
  • Immune function*
  • Joint health*
  • Mood and overall feelings of well-being*
  • Neurological and cognitive health*
  • Muscular function*
  • Skin health*
  • Pancreatic function and health*
  • Healthy aging process*
  • Sleep patterns*
  • Hearing and vision*
  • Reproductive health*
  • Newborn health*
  • Athletic performance*
  • Respiratory function and health*
  • Carbohydrate and fat metabolism*
  • Metabolic rate*
  • Weight management*
  • Hair and hair follicles*

I realize this is a long list. Yet, as research continues on vitamin D, you can expect to see it grow even longer!

What’s YOUR Risk Level for This Hidden Deficiency?

The only way to know for sure if you are vitamin D deficient is to regularly test your blood levels.

Because of vitamin D’s wide-reaching effects in your body, always check to see if you are deficient in this crucial nutrient when addressing any health concern, especially those listed above.

Certain groups of people may be at an increased risk for vitamin D deficiency, as well as individuals with some specific conditions. If any of the following apply to you, please get your vitamin D levels checked sooner than later.

  1. It’s winter and you don’t live in the tropics or subtropics.

There simply isn’t enough, or even any UVB radiation that reaches the ground in the winter if you are not in the tropics or subtropics, and exposure to UVB radiation is how your body produces most of the vitamin D it requires naturally.

  1. You have darker skin.

Those with darker skin may need as much as 10 times more sun exposure to produce the same amount of vitamin D as a person with pale skin.

  1. You’re 50 or older.

As you get older, your skin produces less vitamin D when exposed to the sun.

  1. You spend a lot of time indoors.

If you avoid the sun or just aren’t able to get outdoors regularly, your levels of vitamin D are likely to be lower.

  1. You’re overweight or obese (or have a higher muscle mass).

Vitamin D is a fat-soluble, hormone-like vitamin, so body fat can act like a sponge. A heavier person with more body fat or even those with more muscle mass may require a higher dose than a slimmer person.

  1. You have gut issues.

If you have a gastrointestinal condition that affects your ability to absorb fat you may have lower absorption of vitamin D.

  1. You’re achy or tired, or both.

The classic signs of a certain type of vitamin D deficiency can mimic conditions characterized by fatigue and achy bones.

  1. You sometimes feel “blue.”

Serotonin, the brain hormone associated with mood elevation, rises with exposure to bright light and falls with decreased sun exposure.

  1. You’re pregnant.

Pregnant women require higher amounts of vitamin D for their own pregnancy and delivery as well as the optimal health of their babies.

  1. You notice unusual head sweating.

Surprisingly, one of the first signs of a vitamin D deficiency is a sweaty head.

Please note, I offer vitamin D testing kits in my online store as a convenience for those who don’t have easy access to testing.

A Daily Dose of Sunshine Fixes Everything, Right? Not So Fast…

Your skin naturally produces vitamin D when it’s directly exposed to bright midday sun.

Are you meeting the four conditions for getting enough vitamin D?

But the challenge here is that this is not true in the winter for nearly everyone reading this. Unless you live in the tropics or subtropics, there simply isn’t enough UVB available to you in the winter to make vitamin D.

Even in the summer though, I wish I could tell you that just getting out in the sun takes care of your needs.

It’s certainly my preferred method to produce optimal levels, and research shows it is the most beneficial way to get your vitamin D.

It is one of the primary reasons I moved to Florida. My regular exposure to the sun allows me to keep my vitamin D levels in the healthy range.

However, with the factors I just mentioned – darker skin, over 50, gut issues, and weight – most people simply can’t get enough vitamin D from the sun.

And that’s not all…

To get the vitamin D your body needs for all its cells and tissues, four conditions must be met:

  • You expose large portions of your body, not just your hands and face.
  • You’re outside when UVB rays are at their peak, the only type of rays that produce vitamin D.
  • You avoid the use of sunscreen during UVB exposure as it can prevent your skin from producing vitamin D.
  • You’re in a latitude that has adequate UVB rays.

Many people believe taking a walk during a midday break fulfills their vitamin D needs, but you now know that is usually not true. And of these four conditions, the last one may be the biggest deal breaker of all…

Why You Have a GREATER Chance of Being Deficient Than Not

As you can see from the chart below, in most parts of the US (and the Northern hemisphere, including Canada), you can’t get enough sunlight to produce adequate levels of vitamin D in your skin.

Dr. Michael Holick, a recognized vitamin D expert, has found that if you live north of Atlanta, Georgia in the US, you cannot make vitamin D in your skin from about November through February.

Even as far south as Miami, Florida, you only make about 10 to 20 percent of the vitamin D in winter that you make during the summer months.

One exception to this rule is elevation… At 15,000 feet you can make robust amounts of vitamin D at northern latitudes, mainly because of the sun’s angle and because the sun has less atmosphere to penetrate.

One of the Biggest Mistakes Many People (Including Doctors) Make
with Vitamin D

Here’s another important fact you need to know about vitamin D: Vitamin D3 is not the same as vitamin D2.

Vitamin D3 raises and maintains your blood levels 87 percent better than D2

And taking the wrong one might do you more harm than good.

Vitamin D2 is not the type produced by your body in response to sunlight. The sun stimulates the production of D3, or cholecalciferol.

Ergocalciferol, or vitamin D2, was created in the early 1920s through ultraviolet exposure of plant foods and licensed to pharmaceutical companies.

Today, if you get a prescription from your doctor for vitamin D, it is likely to be this synthetic vitamin D2. It’s easy, even for doctors, to confuse the two forms.

I strongly advise you to avoid vitamin D2. In studies, vitamin D2 actually increasedmortality risk by 2 percent! And it binds poorly with proteins, making it less effective than D3.

Compared to vitamin D2, vitamin D3:

  • Raises and maintains vitamin D3 concentrations 87 percent better
  • Produces 2- to 3-fold greater storage of vitamin D in the body
  • Converts 500 percent faster to the more active form that your body uses

Vitamin D3 is clearly the gold standard. Let’s figure out exactly how much you might need…

The Dangerous Advice That Can Leave You Woefully Deficient

A few years back, the US and Canadian governments asked the Institute of Medicine (IOM) to recommend daily amounts (RDA) of vitamin D for the general population.

They determined that most individuals needed only 600 IUs (International Units) of vitamin D3 to maintain serum levels of 20 ng/ml. And they concluded that everyday foods could provide those levels.

Two Canadian university investigators challenged their findings in 2014 and discovered a drastic error in the IOM’s calculations. They found the RDA for optimal health needs to be at least 10 times greater!

Nearly all vitamin D researchers agree that the recommended range for healthy “average” vitamin D3 levels is 40-60 ng/ml,not 20 ng/ml.

In the chart below, you can see how much vitamin D is needed to achieve various serum levels (top line). For example, if your current level is 20 ng/ml (in the first column), you need a daily dose of 5,000 IUs to raise it to 40, and 10,000 IUs to bring your levels to 60 ng/ml.

VitD chart
Source: Grassroots Health
Depending on your current test values, you may need a substantial dose of vitamin D – 10,000 IUs or more per day – to bring your numbers up into the optimal range.

Additionally there are genetic defects called vitamin D polymorphisms that a number of people have that prevent them from achieving optimum vitamin D levels with the doses described above. They may need many times that dose and the only way to know if you have this problem is to measure your vitamin D level.

So I strongly encourage you let your test values and the chart above be your starting guide for finding your ideal dose of vitamin D3, and not some arbitrary (and grossly inaccurate) numbers published by the government!

For more information on Vitamin D click here.

Autophagy — How Your Body Detoxifies and Repairs Itself

By: Dr. Mercola

Posted 3/9/2016

While there are many different ways to rid your body of accumulated toxins, from detoxifying foods and chemical and/or natural detox agents to saunas, a biological process known as autophagy plays a key role.

The term autophagy means “self-eating,” and refers to the processes by which your body cleans out various debris, including toxins, and recycles damaged cell components.

This video above provides a more in-depth biochemical review of the autophagy processes involved in health and disease. As explained in layman’s terms by Greatist:1

“Your cells create membranes that hunt out scraps of dead, diseased, or worn-out cells; gobble them up; strip ’em for parts; and use the resulting molecules for energy or to make new cell parts.”

Dr. Colin Champ, a board-certified radiation oncologist and assistant professor at the University of Pittsburgh Medical Center explains it thus:

“Think of it as our body’s innate recycling program. Autophagy makes us more efficient machines to get rid of faulty parts, stop cancerous growths, and stop metabolic dysfunction like obesity and diabetes.”

By boosting your body’s autophagy process, you dampen inflammation, slow down the aging process, and optimize biological function. As noted by Fight Aging:2

“Greater autophagy taking place in tissue should mean fewer damaged and disarrayed cells at any given moment in time, which in turn should translate to a longer-lasting organism.”

Boosting Autophagy Through Exercise

Like the benefits of exercise, autophagy occurs in response to stress. And, in fact, exercise is one of the ways by which you boost autophagy. As you probably know, exercising creates mild damage to your muscles and tissues that your body then repairs, and by so doing makes your body stronger.

Exercise also helps flush out toxins by sweating, and is helpful for just about any detox program. In fact, many consider exercise a foundational aspect of effective detoxification.

Dr. George Yu, for example, who has been involved with clinical trials to help detoxify people from the Gulf War, recommends using a combination of exercise, sauna, and niacin supplementation to maximize elimination of toxins through your skin.

Exercise is an important component as it also causes vasodilation and increased blood flow. Beyond that, as noted in the featured article:

“One study looked at autophagosomes, structures that form around the pieces of cells that the body has decided to recycle.

After engineering mice to have glowing green autophagosomes … scientists found that the rate at which the mice were healthily demolishing their own cells drastically increased after they ran for 30 minutes on a treadmill.

The rate continued increasing until they’d been running for 80 minutes.”

How Much Exercise Do You Need to Optimize Autophagy?

The amount of exercise required to stimulate autophagy in humans is still unknown, however it is believed that intense exercise is more effective than mild exercise, which certainly makes logical sense.

That said, other research has shown that the “Goldilocks zone” in which exercise produces the greatest benefit for longevity is between 150 to 450 minutes of moderate exercise per week, lowering your risk of early death by 31 and 39 percent respectively.

Spending at least 30 percent of your workout on high-intensity exercises has also been shown to further boost longevity by about 13 percent, compared to exercising at a consistently moderate pace all the time.

Following these general guidelines will likely put you in the most advantageous position for maximizing autophagy as well.

How to Radically Inhibit Autophagy

One of the quickest ways to shut down autophagy is to eat large amounts of protein. What this will do is stimulate IGF-1 and mTOR, which are potent inhibitors of autophagy.

That is why it’s best to limit your protein to about 40 to 70 grams per day, depending on your lean body mass. The specific formula is one gram of protein for every kilogram of lean body mass, or one-half gram of protein per pound of lean body mass.

Substantial amounts of protein can be found in meat, fish, eggs, dairy products, legumes, nuts, and seeds. Some vegetables also contain generous amounts of protein — for example, broccoli. Forty grams of protein is not a large amount of food — it’s the equivalent of one six-ounce chicken breast.

To determine whether or not you’re getting too much protein, simply calculate your body’s requirement based on your lean body mass, and write down everything you eat for a few days. Then calculate the amount of daily protein you’ve consumed from all sources.

If you’re currently averaging a lot more than what is optimal, adjust downward accordingly. The following chart provides a quick overview of how much protein is in various foods.

Red meat, pork, poultry, and seafood average 6 to 9 grams of protein per ounce.

An ideal amount for most people would be a 3-ounce serving of meat or seafood (not 9- or 12-ounce steaks!), which will provide about 18 to 27 grams of protein

Eggs contain about 6 to 8 grams of protein per egg. So an omelet made from two eggs would give you about 12 to 16 grams of protein

If you add cheese, you need to calculate that protein in as well (check the label of your cheese)

Seeds and nuts contain on average 4 to 8 grams of protein per quarter cup Cooked beans average about 7 to 8 grams per half cup
Cooked grains average 5 to 7 grams per cup Most vegetables contain about 1 to 2 grams of protein per ounce

The Importance of Mitochondrial Biogenesis

Healthy mitochondria are at the core of staying healthy and preventing disease. Mitochondrial damage can trigger genetic mutations that can contribute to cancer, so optimizing the health of your mitochondria is a key component of cancer prevention. Autophagy is one way to remove damaged mitochondria, but biogenesis is the process by which new healthy mitochondria can be duplicated.

Interestingly, exercise plays a dual role as it not only stimulates autophagy but is also one of the most potent stimulators of mitochondrial biogenesis. It does this by increasing a signal in your body called AMPK, which in turn activates PGC-1 alpha.

By stimulating  your mitochondria — the organelles in nearly every cell that produce ATP — to work harder, your mitochondria start making reactive oxygen species (ROS), which act as signaling molecules. One of the functions they signal is to make more mitochondria.

In essence, the key to preventing disease — virtually  eliminating the risk of cancer, heart disease, diabetes, many other diseases — and  slowing down the aging process lies in  optimizing mitochondrial function and increasing mitochondrial numbers. Thankfully, exercise helps you do both.

Intermittent Fasting — Another Way to Boost Autophagy

Fasting is another biological stressor that produces many beneficial results, including autophagy. In fact, some of the benefits associated with fasting — such as a reduced risk of diabetes and heart disease — can at least in part be attributed to this process.

While there are many different kinds of intermittent fasting schedules, if you’re insulin resistant, my personal recommendation is to fast every day by scheduling all of your eating within a window of approximately 8 hours or less. For example, you could restrict your eating to the hours of 11am and 7pm. This equates to 16 hours of daily fasting.

I used to recommend skipping breakfast, but I’ve since realized that it probably doesn’t matter which meal you skip — breakfast or dinner — as long as you skip one of them. Some really struggle without breakfast, so play around with it and find out what works best for you.

Eating between the hours of 8 a.m. and 4 p.m. may work better for some people, and this schedule actually has an added advantage, because you’re now fasting for several hours before going to bed. I’m convinced that it’s best for most to avoid eating three hours prior to bed, as the last thing you need to be doing is producing energy when you don’t need it.

There’s compelling evidence showing that when you supply fuel to your mitochondria at a time when they don’t need it, they leak a large number of electrons that liberate reactive oxygen species as free radicals.

These free radicals damage your mitochondrial and eventually nuclear DNA. There’s also evidence indicating that cancer cells uniformly have damaged mitochondria, so eating too close to bedtime is not a good idea. I personally strive for six hours of fasting before bedtime, but at bare minimum, avoid eating at least three hours before going to bed.

To Boost Autophagy, Switch to a High-Fat, Low-Carb Diet

Nutritional ketogenesis is a third strategy that will help boost autophagy, and to accomplish that, you need to cut down on the non-fiber carbs and increase the amount of healthy fat in your diet, along with a moderate amount of protein. (Many Americans tend to eat far more protein than they need, which will counteract your efforts to get into nutritional ketosis.)  According to Champ:3

“Ketogenesis is like an autophagy hack. You get a lot of the same metabolic changes and benefits of fasting without actually fasting … Between 60 and 70 percent of one’s overall calories should come from [healthy] fat … Protein makes up 20 to 30 percent of calories, while carbs are kept below 50 grams per day …  Similar benefits have been noted in people following a diet in which carbs didn’t exceed 30 percent of their overall calories.”

Most Americans consume harmful fats like processed vegetable oils, which will invariably make your health worse. Not only is it processed, it’s very high in omega-6 oils, and excess omega-6 fats will integrate into the inner mitochondrial membrane and become highly susceptible to oxidative damage, causing your mitochondria to die prematurely.

It is best to keep omega-6 fats consumption to less than 4 to 5 percent of your total daily calories Replace the omega-6 fats with healthy fats-  such as natural, unprocessed fat- found in real foods such as seeds, nuts, real butter, olives, avocado, or coconut oil.

It’s also important to make the distinction about which carbs we’re talking about when we say “low-carb,” as vegetables are “carbs” too. However, fiber carbs (i.e. vegetables) will not push your metabolism in the wrong direction — only the non-fiber ones will (think sugars and anything that converts to sugar, such as soda, processed grains, pasta, bread and cookies, for example).

Even more importantly, the fiber is not broken down by sugar but travels down the digestion system, is consumed by bacteria in your intestine, and converted to short chain fats that actually improve your health.

If you look at the nutrition facts on a processed food package, it will list total carbs, and again, that’s not what we’re talking about. To calculate the dangerous non-fiber carbs, simply subtract the grams of fiber from the grams of total carbohydrate in the food in question. Remember, you do need carbs, but you need most all of them from vegetables, which are also high in fiber.

Autophagy Restores Function in Aging Muscle Stem Cells

It has long been known that mesenchymal stem cells (MSCs) in skeletal muscle are an important part of the muscle repair process. Previous research4 has shown that exercise affects the behavior of your muscle stem cells, and may help prevent or even restore age-related muscle loss. MSCs in muscle are very responsive to mechanical strain, and these stem cells accumulate in muscle post-exercise.

And, while the MSCs do not directly contribute to building new muscle fibers, they do release growth factors, which encourage other cells to generate new muscle. It’s also known that people’s muscles tend to become increasingly deficient in MSCs with age, and that autophagy efficiency declines as well. As a result, metabolic waste starts to build up in your cells and tissues.

A recent Spanish study5 reports that satellite cells — muscle stem cells responsible for tissue regeneration — rely on autophagy to prevent the arrest of the cell cycle, known as cellular senescence; a state in which stem cell activity significantly declines. In short, to improve the regeneration of muscle tissue, you need to augment autophagy.

With efficient autophagy — your body’s internal cleaning mechanism — your stem cells retain the ability to maintain and repair your tissues.

As reported by Fight Aging:6

“The researchers demonstrated that restoring youthful levels of autophagy in old satellite cell populations can restore them from senescence and return their regenerative capabilities … The paper … is one of the more compelling of recent arguments for putting more effort into treatments based on artificially increased levels of autophagy …

[M]any of the methods known to modestly slow aging in laboratory species are associated with increased levels of autophagy. It is a vital component in hormesis, wherein causing a little damage leads to a lasting increase in autophagy and a net gain. Stem cells spend much of their time in a state of quiescence, only springing into action when called upon.

This helps to preserve them for the long term. In older tissues with greater levels of molecular damage, ever more stem cells slip from quiescence into an irreversible senescent state. These senescent cells are no longer capable of generating new cells, and start to secrete all sorts of harmful signal molecules.”

Health and Longevity Are Rooted in Mitochondrial Function

The take-home message here is that your lifestyle determines your fate in terms of how long you’ll live and, ultimately, how healthy those years will be. For optimal health and disease prevention, you need healthy mitochondria and efficient autophagy (cellular cleaning and recycling), and three key lifestyle factors that have a beneficial effect on both are:

  1. What you eat: A diet high in quality fats, moderate in protein, and low in non-fiber carbs. Eating organic and grass-fed is also important, as commonly used pesticides like glyphosate cause mitochondrial damage
  2. When you eat: Daily intermittent fasting tends to be the easiest to adhere to, but any fasting schedule that you willconsistently follow will work
  3. Exercise, with high intensity interval exercises being the most effective

What You Need to Know About B12


B12: Cyanocobalamin vs Methylcobalamin

Posted 3/18/2016

Cyanocobalamin, in summary, is a low-grade, low quality and slightly toxic (due to the cyanide) form of vitamin B12 that’s used by all the cheap vitamin manufacturers.  I recommend avoiding it completely. It won’t kill you to take it, of course, but there’s a better solution for B12.

The better choice: Methylcobalamin

The best form of vitamin B12 to supplement with is called methylcobalamin. This is the form that exists in nature, and it is pre-methylated, meaning it’s ready for your biochemistry to put to immediate use.


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Blood Type Influences Breast Milk

Blood type and secretor status can influence the breast milk of nursing mom’s.

Mom’s secretor status has a lot of influence on the microbiome of her breast-fed child. The principal sugars in human breast milk are rich in the glycan fucose, but milk from non-secretor moms is much lower in its fucose content. Bifidobacterium longum, a critical early colonizer of the gastrointestinal tract of infants, loves fucose, which is why it grows so readily in breast-fed infants of ABO secretor moms. Non-secretor moms who breast feed infants might benefit using a dietary fucose source as a prebiotic for the infant, or consider consuming sea vegetables, such as seaweeds. Since neuronal attachments are largely mediated through fucose-specific lectin ligands, developmental benefits may also result.

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